Acyclovir Tablets | Healthy Inc

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  • Published date: September 14, 2021
    • Mumbai, Alandi, Maharashtra, India [ Ads Views - 4 ]

Aciclovir is an antiviral agent with activity against Herpes simplex virus types 1 and 2, (HSV-1 and HSV-2) and varicella-zoster virus (VZV). Aciclovir is phosphorylated after entry into herpes infected cells to the active compound aciclovir triphosphate. The first step in this process is dependent on the presence of the HSV coded thymidine kinase. Thymidine kinase converts aciclovir into aciclovir monophosphate. The monophosphate is further converted to diphosphate by cellular guanylatekinase and to triphosphate which is the active form of medicine. Aciclovir triphosphate interferes with HSV and VZV DNA polymerase and inhibits viral DNA replication.

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